Welcome to Developmental and Reproductive Biology (DRB) Graduate Program Website!!!

        The Department of Anatomy, Biochemistry and Physiology at the School of Medicine offers a graduate program leading to MS and PhD degrees in Developmental and Reproductive Biology. Students take classes, do laboratory research, and participate in other training activities in our program, which integrates diverse disciplines, such as the study of fertilization, early embryo development, stem cells, assisted reproductive technologies, and animal evolution. Whether your goal is pure basic science or translational research, we offer opportunities that will enable you to impact human health and our understanding of life!

News!!!

Biomedical Sciences Symposium

(04/20/2012)

   Three of our DRB students, Carolyn Higuchi, Brennan Takagi and Arlene Laeno, presented their research projects at the John A. Burns School of Medicine Biomedical Sciences Symposium on April 18, 2012.

    Higuchi C, Maeda Y, Yamazaki Y. Full-term pups derived from oocytes grown in three-dimensional immature ovarian culture
    Takagi B, Hynd TJ, Somponpun SJ, Nonaka K, Lozanoff S. Differential gene expression in the face of CL/Fr mouse embryos at E11.5 based on microarray analysis
    Laeno A, Alarcon V. Embryonic and extra-embryonic tissue segregation in preimplantation development requires ROCK


Attention to Current and Prospective students!!!

    Two important changes have been made to the Program as of October 2011

1. Students can take either CMB621 or CMB622 to fulfill course requirements

    Until Fall 2011, CMB621 was one of the required courses. However, students now have flexibility to take either CMB621 (Fall course) or CMB622 (Spring course) as a part of the course requirements, depending on her/his schedule, interest, and/or career goal. Students are encouraged to consult the Chair, Advisor, or Course Director, to determine which course would be most appropriate.

2. February 15 is the new (and only) deadline for application

    The application deadline has been changed to February 15 (from the previous May 15) for Fall admission. Soon after this deadline, applications will be reviewed by the Graduate Program Committee. Applications for Spring admission is generally not encouraged, but potential applicants may contact the Chairs for more information.

3. Frequently Asked Questions (FAQs) regarding application are listed in Prospective Students page


Recent Publications by DRB students

Ohta K, Yamamoto M, Lin Y, Hogg N, Akiyama H, Behringer RR, Yamazaki Y. Male differentiation of germ cells induced by embryonic age-specific sertoli cells in mice. Biology of Reproduction 2012; 86, 112.

Raunig JM, Yamauchi Y, Ward MA, Collier AC. Placental inflamation and oxidative stress in the mouse model of assisted reproduction. Placenta 2011; 32, 852-858.

Gelber K, Tamura AN, Alarcon VB, Marikawa Y. A potential use of embryonic stem cell medium for the in vitro culture of preimplantation embryos. Journal of Assisted Reproduction and Genetics 2011; 28, 659-668.

Ohta K, Lin Y, Hogg N, Yamamoto M, Yamazaki Y. Direct effects of retinoic acid on entry of fetal male germ cells into meiosis in mice. Biology of Reproduction 2010; 83, 220-227.

Raunig JM, Yamauchi Y, Ward MA, Collier AC. Assisted reproduction technologies alter steroid delivery to the mouse fetus during pregnancy. Journal of Steroid Biochemistry and Molecular Biology 2010; 126:26-34.


Master Defenses

   Arlene Laeno gave a public seminar "Mechanisms of Embryonic and Extra-embryonic Tissue Segregation in Pre-implantation Embryos" on March 16 (Friday) from 10:00am to 11:00am in Kakaako BSB 222P as a part of her Master Defense.

   Hieu Nguyen gave a public seminar "Treatment of Murine Model of Idiopathic Pulmonary Fibrosis Using a Novel Telomerase Activator (TAT0153)" on March 2 (Friday) from 10:00am to 11:30am in Manoa IBR Conference Room Biomed E125 as a part of her Master Defense.

   Karra Imoto gave a public seminar "Quantitative Assessment of the Human Pharynx Based on Cone Beam Computed Tomography" on September 26 (Monday) from 1:00pm to 2:00pm in Kakaako BSB 222N as a part of her Master Defense.

   Nathanael (Nate) Hogg gave a public seminar "Sex-Specific Gene Knockdown in Mouse Fetal Germ Cells" on May 19 (Thursday) from 10:30am to 11:30am in Kakaako BSB 222N as a part of his Master Defense.

   Nora Matutino-Phillips gave a public seminar "Examination of the Effects of siRNA to Six2 on Embryonic Kidneys ex vivo" on May 4 (Wednesday) from 9:00am to 10:00am in Kakaako BSB 222N as a part of her Master Defense.

   Aileen Tamura gave a public seminar "Mechanism of Meiotic Spindle Disappearance and Regeneration during Oocyte Vitrification" on March 11 (Friday) in Kakaako BSB 222N from ~9:30am, as a part of her Master Defense. This was the day when the tsunami warning was issued, and all classes at UH were canceled. Nonetheless, many people, including several DRB students and faculty members, showed up for her seminar, and we decided to proceed as originally scheduled. We apologize for those students, faculty members and others, who wished to attend the seminar but were unable to do so due to transportation problem, communication problem, and other issues caused by the tsunami warning.